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    Home»Tech News»19 of the Absolute Best Sci-Fi TV Shows on Prime Video
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    19 of the Absolute Best Sci-Fi TV Shows on Prime Video

    Michael ComaousBy Michael ComaousSeptember 5, 2025No Comments9 Mins Read0 Views
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    Prime Video has sci-fi TV shows you’re looking for. I know that sounds like hyperbole, but stick with me here. You’re probably used to finding the must-watch genre shows at places like Netflix, Disney Plus and even Apple TV Plus. Those streaming services are packed with good stuff, but the Amazon-owned streamer should not be slept on.

    When it comes to programming, each streamer seems to have a specific brand that their shows adhere to. For Prime Video, that vibe is cutting-edge, forward-thinking, satirical type. Take titles like The Man in the High Castle, Outer Range or The Boys. Each one offers thought-provoking narratives that you can unravel in layers.

    If you’d rather not put your brain through the ringer, there are lighter options on the platform, too. You can find a cool animated anthology, a futuristic rom-com and a tech-inspired comedy about the afterlife from the creator of The Office in the below roundup of the streamer’s best sci-fi shows. 

    Don’t take my word for it, read on for our guide to the best sci-fi shows on Prime Video right now.


    Don’t miss any of our unbiased tech content and lab-based reviews. Add CNET as a preferred Google source.


    Read more: Prime Video: The 29 Absolute Best Shows to Watch

    JoJo Whilden/Prime Video

    Fallout is a fun, kinetic, action-packed video game adaptation that upholds the vibe of Bethesda’s iconic franchise while also charting a new course, story-wise. You don’t need to be familiar with the games to enjoy this show. Sure, there are loads of cool Easter eggs for fans to appreciate. But Fallout was made with a broader audience in mind. And thanks to the killer performances by the cast — Walton Goggins and Ella Purnell are perfect — and the detailed world-building, you won’t want to miss taking this wild ride into the Wasteland.

    Prime Video

    The Second Best Hospital in the Galaxy

    If you’re looking for a hospital drama with otherworldly flair, may I suggest giving The Second Best Hospital in the Galaxy a spin? It’s like Grey’s Anatomy if every patient were from another planet — which, of course, means all sorts of odd conditions and neuroses to deal with. It’s funny, heartfelt and original, which ticks all the boxes for me.

    Prime Video

    Secret Level hails from the creators of the animated anthology hit Love, Death and Robots. Each episode is inspired by a different video game, expanding the story world to provide newbies and hardcore gamers with new adventures to revel in. Dungeons & Dragons, Pac-Man, Warhammer 40,000 and Mega Man are just a few of the games featured in the show.

    Sophie Mutevelian/Prime Video

    Cyberpunk icon William Gibson wrote the novel that inspired The Peripheral. Created by Jonathan Nolan and Lisa Joy — the duo that brought Westworld and Fallout to the small screen — the series stars Chloë Grace Moretz as Flynne Fisher, a woman who becomes involved in a reality-bending virtual reality video game. A trip to future London and an unexpected mission to save the world flip her life, and this series, on its head.

    Liane Hentscher/Prime Video

    From The Office to Parks and Recreation and The Good Place, Greg Daniels has extensive experience bringing game-changing comedies to the small screen. In Upload, he brings his quirky sensibilities to the afterlife with a program that posits that, in the near future, tech companies will offer virtual resorts where the consciousnesses of the recently deceased can enjoy a heavenly forever vacation. That is, of course, if they can afford it. 

    Amazon Studios

    The Expanse is The Little Engine That Could of science fiction TV shows. The series explores a future reality where humanity successfully colonized the solar system. It began as a scripted original series on SyFy but after three seasons, the network dropped the ax on the program. Thankfully, Amazon swooped in to save it from cancellation. Over its six-season run, the series found its legs and audience, blossoming into an intelligent, riveting sci-fi drama.

    Amazon Studios

    A few years after Garth Ennis’s Preacher achieved mild success on AMC, the writer’s famous superhero comic The Boys touched down on Prime Video and blew the doors off. In the series, a group of corrupt celebrity superheroes grapple for power and fame as a gang of outlaws (aka The Boys) hunts them down individually. It’s a violent spectacle that smacks the audience in the face with a heaping helping of social and political commentary. And it’s quite good, too.

    Read our review of The Boys.

    Brooke Palmer/Prime Video

    As powerful, violent and bewildering as its parent series The Boys, Gen V shines a light on the next generation of genetically altered superheroes. The usual social and political tropes are on display here. Additionally, Gen V digs into topics like the influence of social media, body image, classism and race in the realm of higher education. 

    Amazon Studios/YouTube/CNET Screenshot

    Inspired by the narrative art book by Swedish retro-futuristic artist Simon Stålenhag, the series balances the sleek aesthetic of a tech-heavy future world with the quiet quaintness of rural America. Jonathan Pryce and Rebecca Hall deliver standout performances in this quirky, slow-burn sci-fi series.

    Karen Kuehn/Amazon Studios

    If Yellowstone and The X-Files had a baby, it’d probably be Outer Range. The sci-fi Western follows Royal Abbott (Josh Brolin), the patriarch and owner of the Abbott family ranch. His family lives in the wake of the unexplained disappearance of his daughter-in-law. When a stranger comes to stay with the family, Royal must reckon with his past, present and potential future. This would be it if you’re looking for a trippy series grounded in its writing and stellar performances.

    Read our Outer Range review.

    Amazon Studios

    The Man in the High Castle

    What if America didn’t win World War II? That’s the central question The Man in the High Castle aims to answer. Based on Philip K. Dick’s novel of the same name, the series takes place in the 1960s and presents an alternate reality where Nazi Germany and Japan share control of the US. When newsreel footage from an alternate timeline where Germany and Japan lost the war surfaces, the seeds of rebellion are planted. Ridley Scott executive produced the poignant, thought-provoking series.

    Elizabeth Sisson

    Philip K. Dick’s Electric Dreams

    Bryan Cranston (Breaking Bad), Ronald D. Moore (Battlestar Galactica) and Michael Dinner (Justified) came together to bring Philip K. Dick’s Electric Dreams to life. The futuristic anthology series explores how technology can impact humanity in various fantastic and horrific ways. Narrative similarities between Electric Dreams and Black Mirror most certainly abound. However, each episode of the Prime Video program takes inspiration from the work of the titular sci-fi author.

    Chuck Hodes/Amazon Studios

    Thematically, Night Sky feels reminiscent of Close Encounters of the Third Kind and Cocoon. The slow-burn series, which lasted only one season, stars J.K. Simmons and Sissy Spacek as an aging married couple grappling with the trials and tribulations of their golden years. Also, a mysterious portal to a strange planet exists beneath their shed. This sentimental mystery box series explores aging and mortality in a surprisingly heartfelt way — thanks to the engaging performances of the two leads.

    Amazon Studios

    Inspired by Robert Kirkman’s comic series of the same name, Invincible follows Mark Grayson (Steven Yeun), an ordinary high school kid who happens to be the son of Omni-Man (J.K. Simmons) — the most powerful superhero on the planet. When Mark exhibits special abilities, he discovers the unfortunate truth about who his father is and the insidious things he’s done. This animated series is beautifully designed, well-written and wonderfully acted. It’s seen by many as the best superhero show on TV, and for good reason. 

    Katie Yu/Prime Video/Amazon Studios

    In The Power, Prime Video’s series based on Naomi Alderman’s 2016 novel of the same name, teenage girls all over the globe suddenly develop the ability to shoot electricity from their hands. How exactly does this superpower change the female experience in America and beyond? Toni Collette and Jon Leguizamo star alongside a cast of talented young women in a series that aims to flip gender tropes and dynamics on their heads.

    Prime Video/Amazon Studios

    It’s easy to compare Paper Girls to Stranger Things. Parts of the story take place in the ’80s and follow a group of kids struggling to make sense of a supernatural event in town as they ride around on their bikes. The similarities end there, though. Based on the Brian K. Vaughn comic books of the same name, the one-season program kicks off when our 12-year-old paper delivery girls face their future selves and fight for survival amid a time travel war that unfolds around them.

     

    Niko Tavernise/Prime Video

    Prime Video took a big swing with Dead Ringers. This updated twist on David Cronenberg’s cult horror classic finds Rachel Weisz in the dual-starring role as doctors Elliott and Beverly Mantle. Their drive to push the health care envelope throws medical ethics to the wind. The result is a program that never shies away from exploring topics like big pharma’s control over women’s health, antiquated reproductive practices, body autonomy and so much more.

    Amazon Studios

    The rotoscoping animation used in Undone offers a dreamlike tapestry for the audience to take in. One could easily view the show as an ethereal work of art but there’s also deep substance here. The show follows Alma (Rosa Salazar), a troubled 20-something whose life is turned on its head after she suffers an accident. As her reality shatters itself into something else, she must fight to make sense of her trauma. Part mystery, part thriller and part family drama — it’s safe to say that Undone is unlike any TV show you’ve seen before.

    Jessica Miglio/Amazon Studios

    Not to be confused with the short-lived sitcom starring Patrick Warburton, this live-action take on the blue superhero with wiggly antennae is more extensive, more action-packed and takes the comic book genre it’s parodying a bit more seriously. Ben Edlund, the creator of the original comic and 2001 TV series, executive produced this iteration of the character, ensuring the program’s sense of humor and vibe stayed true to his original vision. Peter Serafinowicz and Griffin Newman have a wonderful chemistry together. Jackie Earle Haley’s villainous portrayal of The Terror is an absolute delight. It makes the three-season series a must-watch for any comic book fans.

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